ZyndaClin Oral Drops contain clindamycin hydrochloride which is the hydrate salt of clundamycin. Clindamycin is a semisynthetic antibiotic produced by a 7(S)-chlorosubstitution of the 7(R)-hydroxly group of a naturally produced antibiotic produced by Streptomyces lincolnensis var. lincolnensis.
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ZyndaClin Oral Drops contain clindamycin hydrochloride which is the hydrate salt of clundamycin. Clindamycin is a semisynthetic antibiotic produced by a 7(S)-chlorosubstitution of the 7(R)-hydroxly group of a naturally produced antibiotic produced by Streptomyces lincolnensis var. lincolnensis.
ZydaClin Oral Drops is a palatable formulation intended for oral administration.
ZydaClin Oral Drops (for use in dogs and cats) are indicated for the treatment of infections caused by susceptible strains of the designated microorganisms in the specific conditions listed below:
Dogs: Skin infections (wounds and abscesses) due to coagulase positive staphylococci (Staphylococcus aureus or Staphylococcus intermedius). Deep wounds and abscesses due to Bacteroides fragilis, Prevotella melaninogenicus, Fusobacterium necrophorum and Clostridium perfringens.
Dental Infections: due to Staphylococcus aureus, Bacteroides fragilis, Prevotella melaninogenicus, Fusobacterium necrophorum and Clostridium perfringens. Osteomyelitis due to Staphylococcus aureus, Bacteroides fragilis, Prevotella melaninogenicus, Fusobacterium necrophorum and Clostridium perfringens.
Cats: Skin infections (wounds and abscesses) due to Staphylococcus aureus, Staphylococcus intermedius, Streptococcus spp. Deep wounds and abscesses due to Clostridium perfringens and Bacteroides Fragilis.
Dental Infections: due to Straphylococcus aureus, Staphylococcus intermedius, Streptococcus spp., Clostridium perfringens and Bacteroides fragilis.
| Directions | Dogs:Infected Wounds, Abscesses and Dental InfectionsOral: 2.5-15.0 mg/lb body weight every 12 hours. Duration: Treatment with ZydaClin Oral Drops may be continued up to a maximum of 28 days if clinical judgment indicates. Treatment of acute infections should not be continued for more than three or four days if no response to therapy is seen. Dosage Schedule:ZydaClin Oral Drops, administer 1-6 mL/10 lb body weight every 12 hours. OsteomyelitisOral: 5.0-15.0 mg/lb body weight every 12 hours. Duration: Treatment with ZydaClin Oral Drops is recommended for a minimum of 28 days. Treatment should not be continued for longer the 28 days if no response to therapy is seen. Dosage Schedule:Zydaclin Oral Drops, administer 2-6 mL/10 lb body weight every 12 hours. Cats:Infected Wounds, Abscesses and Dental InfectionsOral: 5.0-15.0 mg/lb body weight every 24 hours depending on the severity of the condition. Duration: Treatment with ZydaClin Oral Drops may be continued up to a maximum for a minimum of 14 days if clinical judgment indicates. Treatment of acute infections should not be continued for more than three to four days if no clinical response to therapy is seen. Dosage Schedule:ZydaClin Oral Drops, to provide 5.0 mg/lb administer 1 mL/body weight once every 24 hours; to provide 15.0 mg/lb administer 3 mL/5 lb body weight once every 24 hours. Caution:Federal Law restricts this drugs to use by or on the order of a licensed veterinarian. Contraindications:ZydaClin Oral Drops are contraindicated in animals with a history of hypersensitivity to preparations containing clindamycin or lincomycin. Because of potential adverse gastrointestinal effects, do not administer to rabbits, hamsters, guinea pigs, horses, chinchillas or ruminating animals. Human Warnings:Keep out of reach of children. Not for human use. Precautions:During prolonged therapy of one month or greater, periodic liver and kidney function tests and blood counts should be performed. The use of ZydaClin Oral Drops occasionally results in overgrowth of non-susceptible organisms such as clostridia and yeasts. Therefore, the administration of ZydaClin Oral Drops should be avoided in those species sensitive to the gastrointestinal effects of clindamycin (see Contraindications). Should super infections occur, appropriate measures should be taken as indicated by the clinical situation. Patients with very severe renal disease and/or very severe hepatic disease accompanied by severe metabolic aberrations should be dosed with caution, and serum clindamycin levels monitored during high dose therapy. Clindamycin hydrochloride has been shown to have neuromuscular blocking properties that may enhance the action of other neuromuscular blocking agents. Therefore, ZydaClin Oral Drops should be used with caution in animals receiving such agents. Safety in gestating bitches and queens or breeding male dogs and cats has not been established. Adverse ReactionsSide effects occasionally observed in either clinical trials or during clinical use were vomiting and diarrhea. To report a suspected adverse reaction or to request a Safety Data Sheet (MSDS) call 1-800-524-6332 Storage:Store at controlled room temperature 20°-25°C (68°-77°F)[see USP]. |
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