Nobivac Puppy-DPv (Progard Puppy DPC) 25x1

Intervet/Schering-Plough Animal Health

Canine Distemper-Parvovirus Vaccine

Modified Live Virus

For Use In Dogs Only

Product Description: PROGARD^® PUPPY-DPv is a modified live virus vaccine containing attenuated strains of canine distemper virus and parvovirus grown in the PRO-CELL STABLE CELL LINE™. PROGARD^® PUPPY-DPv is presented in a desiccated, single dose form with sterile diluent provided for reconstitution.

The attenuated distemper virus strain used in PROGARD^® PUPPY-DPv is the Onderstepoort strain. The parvovirus component is patented* CPV STRAIN 154^® which is an attenuated parvovirus strain of canine origin. The unique InterTek™ production process has made it possible to produce PROGARD^® PUPPY-DPv with high titered CPV and CDV components which are highly immunogenic.

Indications: PROGARD^® PUPPY-DPv is for vaccination of healthy dogs against canine distemper virus infection and canine parvovirus infection.

Safety and Efficacy: The safety, efficacy and compatibility of each of the components of PROGARD^® PUPPY-DPv have been demonstrated to meet or exceed the standards set forth by the U.S.D.A. In challenge studies, CPV STRAIN 154^® prevented virulent CPV infection and subsequent lymphopenia and excretion of virulent CPV in 100% of the vaccinates. Severe clinical signs and lymphopenia, accompanied by excretion of virulent CPV, were present in 100% of the control dogs. Severity of challenge was evident in the control dogs for both CPV and CDV challenge studies. Clinical signs of CPV and CDV infections were prevented in 100% of the vaccinates.

Directions for Use: Aseptically reconstitute the desiccated vaccine with the sterile diluent provided and administer 1 mL by subcutaneous or intramuscular route. Initial vaccination of healthy dogs may be given as early as 4 weeks of age with booster injections administered every 3-4 weeks until 12 weeks of age. Dogs over 12 weeks of age should initially receive 2 doses 3-4 weeks apart. Annual revaccination with a single dose is recommended.

Precautions:

1. Recommended storage temperature 35-45°F (2-7°C).

2. Shake well before use.

3. Use contents promptly once reconstituted.

4. Non-chemically sterilized needles and syringes should be used for administration of vaccine.

5. Avoid vaccinating pregnant bitches.

6. Administration of epinephrine may be indicated in the event of an anaphylactic reaction.

7. Contains gentamicin and amphotericin B as preservatives.

8. Burn this container and all unused contents.

9. Only healthy animals should be vaccinated. Animals incubating any disease, or animals stressed due to shipping, malnutrition or parasitism may not achieve or maintain an adequate immune response.

10. This product is not hazardous when used according to directions supplied. A material safety data sheet (MSDS) is available upon request. This and any other consumer information can be obtained by calling Intervet's Customer Service Department at 1-800-441-8272.

Supplied: Cartons of 25-1 dose desiccated vaccine vials and 25 - 1 ml sterile diluent vials. Packaged in recyclable plastic containers.

Sales Product Code No. C-672-1

FOR VETERINARY USE ONLY

U.S. VETERINARY LICENSE NO. 286

INTERVET INC., 405 State Street, Millsboro, DE 19966

Rev. 40274004

*U.S. Patent No. 4,810,494

AL 302

CPN: 1106132.1