NeoPar at a glance
| Product | NeoPar® Parvovirus Vaccine, Modified Live Virus |
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| Manufacturer | NeoTech, LLC, Dresden, Tennessee (U.S. Veterinary License No. 472, product code 18M1.20) |
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| Protects against | Canine parvovirus (single-antigen vaccine) |
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| Species | Dogs only |
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| Dose | 1 mL |
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| Route | Subcutaneous (SC) or intramuscular (IM) injection |
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| First dose | At or about 42 days of age |
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| Puppy series | Revaccinate every 14 to 21 days until 18 weeks of age |
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| Dogs over 18 weeks | A single 1 mL dose |
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| Booster | Revaccinate annually with one dose |
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| Storage | 2° to 7°C (35° to 45°F). Do not freeze. |
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| Preservatives | Gentamicin and amphotericin B |
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| Pack options | Single-dose vials (1, 6 or 25) and 10-dose vials (1 or 10) |
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What NeoPar is
NeoPar is a modified live virus vaccine against canine parvovirus, made by NeoTech, LLC in Dresden, Tennessee. It contains only one antigen: parvovirus. It is not a 5-way or 7-way combination, so you can schedule parvo protection on its own rather than tie it to a combination shot.
NeoTech describes canine parvovirus as “the most lethal and prevalent viral disease of dogs.” For anyone raising litters, managing a kennel or taking in shelter puppies, parvo is the disease that can move through a whole group at once. That is why many operations want a dedicated parvo vaccine on the shelf.
Why breeders, kennels and shelters use a single-antigen parvo vaccine
NeoTech states the following about NeoPar on its official product page:
- High antigen mass. NeoPar “contains a High Antigen Mass (more vaccine units per dose),” which NeoTech says gives a short period from vaccination to protection, a higher level of protection and a long duration of immunity.
- Works with maternal antibody present. NeoTech states NeoPar “stimulates antibody production in the presence of existing maternal antibodies.”
- Antibody response after the first dose. According to NeoTech, “antibody production begins after the first dose.”
- No extra antigens. NeoTech positions NeoPar as a way to avoid using complex combination adult vaccines (commonly called 5-way vaccines) in the young puppy.
- Safety. NeoTech reports NeoPar was “found to be safe for use in young puppies.”
Those are the manufacturer's statements. The label directions below are what we follow and what you should follow.
NeoTech's early-age antibody study
For years, the objection to vaccinating very young puppies was that no one could show an antibody response that early, especially with maternal antibody still present. NeoTech tested it. In an internal NeoTech study, 52 puppies between 18 and 21 days of age each received a single 1 mL dose of NeoPar. Ninety percent showed a positive vaccine-induced canine parvovirus antibody response after that one dose, across maternal antibody titers ranging from 32 to 3,162. That range runs from puppies with almost no maternal protection to puppies carrying very high levels of it.
What the study shows: a measurable antibody response can be produced at that age, and it can be produced in the presence of maternal antibody. That is the reason NeoPar's high antigen mass matters for litters. Timing your own program is still a label and veterinary decision: the NeoPar label calls for the initial dose at or about 42 days of age, with revaccination every 14 to 21 days until 18 weeks.
Source: NeoTech, LLC internal study data, as provided by the manufacturer.
Does vaccinating weekly cause “immune confusion”?
Commercial kennels that place puppies at 8 weeks often can't keep a 2 to 3 week gap between every vaccine, and some people claim that vaccinating more often leaves a puppy unprotected. NeoTech checked. Twenty commercial-kennel puppies followed a weekly schedule that alternated NeoPar (at 35 and 49 days) with NeoVac DA2 (at 42 and 56 days), along with a routine parasite control program. Blood was drawn at about 8½ weeks and tested for canine parvovirus antibody by serum neutralization.
A parvovirus titer of 80 is recognized in the scientific literature as protective against viral challenge. All 20 puppies were above that level, with titers from 100 to more than 5.6 million. Eight of the 20 had titers of 100,000 or more, at least 1,250 times the protective level. NeoTech's conclusion: its weekly schedule alternating NeoPar and NeoVac DA2 induces a robust level of protection in 8-week-old puppies.
Source: NeoTech, LLC internal serological study, as provided by the manufacturer.
Who NeoPar is for, and who should not get it
NeoPar is labeled for healthy dogs, starting with puppies at or about 42 days (6 weeks) of age, and for dogs over 18 weeks that need a single dose. Typical buyers are breeders vaccinating litters, kennels keeping adult dogs current, and shelters and rescues vaccinating new intakes.
Per the label, do not vaccinate:
- Pregnant bitches
- Sick dogs
- Debilitated dogs
NeoPar is for use in dogs only. It is not labeled for cats or any other species.
How to give NeoPar (label directions)
- Shake well before using.
- Aseptically inject 1 mL subcutaneously (SC) or intramuscularly (IM) into a healthy dog.
- Give the first dose at or about 42 days of age.
- Maternal antibody can interfere with the immune response to the first vaccination, so revaccinate every 14 to 21 days until the dog is 18 weeks of age.
- Dogs over 18 weeks of age should receive a single 1 mL dose.
- Revaccinate annually with one dose.
Use the entire contents of a vial when first opened. For a 10-dose vial, that means planning to vaccinate ten dogs in one session. If you vaccinate fewer dogs at a time, single-dose vials avoid waste.
Your veterinarian can help you build a vaccination program that fits your animals. If anything on this page differs from the label on the vial you receive, follow the label.
Storage and handling
- Store between 2° and 7°C (35° and 45°F), which is standard refrigerator temperature.
- Do not freeze.
- Shake well before using.
- Use entire contents when first opened.
- Burn the container and all unused contents.
Pack sizes
| Option | What you get | Best for |
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| Single dose | 1 single-dose vial (1 mL) | One dog, or a top-up |
| 6 × single-dose vials | 6 vials, 1 mL each | A small litter |
| 25 × single-dose vials | 25 vials, 1 mL each | Kennels that vaccinate a few dogs at a time |
| 10-dose vial | 1 vial, 10 mL (10 doses) | Vaccinating 10 dogs in one session |
| 10 × 10-dose vials | 10 vials, 100 doses total | Large kennels and shelters |
A 10-dose vial costs less per dose than single-dose vials. Because the label says to use the whole vial once it is opened, pick the format that matches how many dogs you vaccinate at one time. Current prices for every option are shown above.
The label calls for clean technique, so you will need a needle and syringe for each dog. See our syringe and needle combos.
How we ship vaccines
From our shipping policy:
- We ship vaccines and perishable items Monday through Wednesday. Orders received by 1 pm EST go out the same day.
- Vaccines ship UPS 2nd Day Air, packed in a styrofoam vaccine shipping cooler with 3 ice packs. The cooler and 3 ice packs are included at no extra charge. Extra ice packs beyond 3 can be added for a fee.
- The ice packs will often have melted by the time the box arrives. That means the packaging did its job. The cooler and ice packs protect the vaccine from big temperature swings in transit; they are not meant to deliver it at refrigerator temperature. Put the vaccine in the refrigerator as soon as it arrives.
- Overnight shipping is available on request: note it at checkout or call 800-979-2869.
- Vaccines and other perishable items cannot be returned or refunded.
Frequently asked questions
What does NeoPar protect against?
Canine parvovirus only. NeoPar is a single-antigen modified live parvovirus vaccine. It does not cover distemper or adenovirus. NeoTech makes those in a separate vaccine, NeoVac DA2.
How old does a puppy have to be for NeoPar?
The label says to give the first dose at or about 42 days of age (about 6 weeks).
How many doses does a puppy need?
After the first dose, the label says to revaccinate every 14 to 21 days until the puppy is 18 weeks old, then once a year.
Does NeoPar work when a puppy still has maternal antibodies?
NeoTech states NeoPar stimulates antibody production in the presence of maternal antibodies. In an internal NeoTech study, 90% of 52 puppies aged 18 to 21 days showed a positive parvovirus antibody response after a single 1 mL dose, across maternal antibody titers from 32 to 3,162. Follow the label schedule for your own vaccination program.
Can I alternate NeoPar and NeoVac DA2 weekly?
In a NeoTech serological study, 20 commercial-kennel puppies vaccinated weekly, alternating NeoPar at 35 and 49 days with NeoVac DA2 at 42 and 56 days, all had parvovirus titers above the protective level of 80 at about 8.5 weeks of age, ranging from 100 to over 5.6 million. Talk with your veterinarian about the schedule that fits your kennel.
Why does the label call for repeat doses?
The label explains that maternal antibody passed from the dam can interfere with the puppy's response to the first vaccination. Repeating the dose every 14 to 21 days until 18 weeks covers that window.
What about an adult dog with an unknown vaccine history?
The label says dogs over 18 weeks of age should receive a single 1 mL dose, then be revaccinated annually with one dose.
Can I give NeoPar to a pregnant dog?
No. The label says not to vaccinate pregnant bitches, sick dogs or debilitated dogs.
Can I use NeoPar in cats?
No. NeoPar is labeled for use in dogs only.
How should NeoPar be stored?
In the refrigerator, between 2° and 7°C (35° and 45°F). Do not freeze it. Shake well before use.
Can I save part of a 10-dose vial for later?
No. The label says to use the entire contents when first opened. If you are vaccinating fewer than ten dogs at once, choose single-dose vials.
What preservatives does NeoPar contain?
The label lists gentamicin and amphotericin B as preservatives.
What if a dog has a reaction?
The label states that in case of anaphylaxis, epinephrine, corticosteroids and antihistamines may be indicated depending on the nature and severity of the reaction. Contact your veterinarian right away if you see signs of a reaction.
How do you ship vaccines?
Vaccines ship UPS 2nd Day Air, packed in a styrofoam vaccine shipping cooler with 3 ice packs. The cooler and 3 ice packs are included at no extra charge. Extra ice packs beyond 3 can be added for a fee. Vaccine shipping is a flat rate by zone:
| Zone 1: $29.99 | KS, WI, OK, IL, LA, MI, AR, IN, MO, KY, IA, TN, MS, AL, GA, FL, SC, NC, VA, WV, PA, OH |
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| Zone 2: $39.99 | CT, MA, NJ, NY, RI, TX, VT, DE, MD |
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| Zone 3: $69.99 | CO, NM, NE, SD, ND, MN, CA, UT, NV, WY, AZ, MT, ID, WA, OR, ME, NH |
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| Other states (including AK and HI) | Call 800-979-2869 for a rate |
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Overnight shipping is available for an additional charge: note it in the order comments at checkout or call 800-979-2869.
The ice packs were melted when my order arrived. Is the vaccine OK?
Melted ice packs are expected. The packaging protects the vaccine from large temperature swings during the 2-day trip; it is not designed to arrive at refrigerator temperature. Refrigerate the vaccine as soon as it arrives. Overnight shipping is available on request: note it at checkout or call 800-979-2869.
Can I return vaccines?
No. Vaccines and other perishable items cannot be returned or refunded.
Who makes NeoPar?
NeoTech, LLC of Dresden, Tennessee, under U.S. Veterinary License No. 472. The USDA lists NeoPar as product code 18M120, “Parvovirus Vaccine, Modified Live Virus,” for canine use.
Why buy NeoPar from A to Z Vet Supply
- Close to the source. We are at 9876 Hwy. 22 in Dresden, Tennessee, on the same highway as NeoTech's facility.
- Every size on one page. Single-dose vials and 10-dose vials, from 1 dose up to 100 doses.
- Real people on the phone. Call 800-979-2869, Monday through Friday, 8 am to 5 pm Central.
- Cooler and 3 ice packs included at no extra charge on every vaccine order, shipped UPS 2nd Day Air as described above.
Label information
From the NeoPar label (10 mL / 10-dose vial):
Parvovirus Vaccine, Modified Live Virus. For use in dogs only. NeoPar®. U.S. Veterinary License No. 472. Product code: 18M1.20. NeoTech, LLC, Dresden, TN 38225 USA.
Dosage: Aseptically inject 1 ml SC or IM into healthy dogs. Administer the initial dose at or about 42 days of age. Because there is potential for maternal antibody to interfere with the immune response to the original vaccination, revaccinate every 14 to 21 days until the dog is 18 weeks of age. Dogs over 18 weeks of age should receive a single dose (1ml). Revaccinate annually with one dose.
Precautions: Store between 2° and 7° C (35° and 45° F). Do not freeze. Shake well before using. Use entire contents when first opened. Do not vaccinate pregnant bitches, sick, or debilitated dogs. In case of anaphylaxis; epinephrine, corticosteroids, and antihistamines may be indicated depending on the nature and severity of the reaction. Gentamicin and Amphotericin B used as preservatives. Burn this container and all unused contents.
FOR VETERINARY USE ONLY.
This page summarizes the manufacturer's label and published product information. Always read and follow the label on the product you receive, and consult your veterinarian about the right vaccination program for your animals.
